Chemicals and Drugs

Glial Cell Line-Derived Neurotrophic Factor

The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.

MeSH Record

Classification

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MeSH Record

Synonyms

11 entry terms
  • GDNF
  • GDNF Growth Factor
  • Glial Cell-Derived Neurotrophic Factor
  • Glial Cell-Line Derived Neurotrophic Factor
  • Glial-Derived Neurotrophic Factor
  • Factor, Glial-Derived Neurotrophic
  • Glial Cell Derived Neurotrophic Factor
  • Glial Cell Line Derived Neurotrophic Factor
  • Glial Derived Neurotrophic Factor
  • Growth Factor, GDNF
  • Neurotrophic Factor, Glial-Derived

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS is also available

MeSH Record

History Note

2006(1993)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Glial Cell Line-Derived Neurotrophic Factor. Medical Subject Headings (MeSH). 2026. Unique ID D051100. http://id.nlm.nih.gov/mesh/2026/D051100
  2. Glial Cell Line-Derived Neurotrophic Factor. In: Wikidata. https://www.wikidata.org/wiki/Q24788019