Chemicals and Drugs

Gingipain Cysteine Endopeptidases

Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.

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MeSH Record

Synonyms

22 entry terms
  • Gingipain
  • Gingipain Proteases
  • Gingipains
  • Cysteine Endopeptidases, Gingipain
  • Arg-Gingipain
  • Argingipain
  • Arginine Gingipain
  • Gingipain K
  • Gingipain R
  • Gingipain R1
  • Gingipain R2
  • KGP Protease
  • Lys-Gingipain
  • Lysine Gingipain
  • RGP-2 Gingipain
  • RGPB Protein
  • Arg Gingipain
  • Gingipain, Arginine
  • Gingipain, Lysine
  • Gingipain, RGP-2
  • Lys Gingipain
  • RGP 2 Gingipain

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Cysteine Endopeptidases (1992-2019)

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AMA Style

References

  1. National Library of Medicine. Gingipain Cysteine Endopeptidases. Medical Subject Headings (MeSH). 2026. Unique ID D000080867. http://id.nlm.nih.gov/mesh/2026/D000080867
  2. Gingipain Cysteine Endopeptidases. In: Wikipedia. https://en.wikipedia.org/wiki/Gingipain
  3. Gingipain Cysteine Endopeptidases. In: Wikidata. https://www.wikidata.org/wiki/Q5563103