Chemicals and Drugs

Gestrinone

A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.

Chemical Identity

Chemical Information

Molecular Formula
C21H24O2
Molecular Weight
308.4 g/mol
CAS Registry No.
16320-04-0
IUPAC Name
(8S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey
BJJXHLWLUDYTGC-ANULTFPQSA-N
SMILES
CC[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(C#C)O
MeSH Unique ID
D005867
Source
PubChem CID 27812

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 18,19-Dinorpregna-4,9,11-trien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17alpha)-
  • Dimetriose
  • Nemestran
  • R-2323
  • R2323
  • R 2323

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(88); was see under NORPREGNATRIENES 1988-90; was R 2323 see under NORPREGNATRIENES 1979-87

MeSH Record

Previous Indexing

  • Gonanes (1968-1974)
  • Norgestrienone/analogs & derivatives (1975-1978)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.668w.651.568.620w.400w

AMA Style

References

  1. National Library of Medicine. Gestrinone. Medical Subject Headings (MeSH). 2026. Unique ID D005867. http://id.nlm.nih.gov/mesh/2026/D005867
  2. Gestrinone. In: Wikipedia. https://en.wikipedia.org/wiki/Gestrinone
  3. Gestrinone. In: Wikidata. https://www.wikidata.org/wiki/Q3761406
  4. Gestrinone. In: PubChem Compound. CID 27812. https://pubchem.ncbi.nlm.nih.gov/compound/27812