Chemicals and Drugs

Gelsolin

A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Gelsolin Protein
  • Serum Actin Inhibitory Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1994(1980)

MeSH Hierarchy

Tree Numbers

  1. D05.750w.078w.730.350w
  2. D12.644w.360.372w.437w
  3. D12.776w.157w.125w.412w.437w
  4. D12.776w.220.525.350w
  5. D12.776w.476.387w.437w

AMA Style

References

  1. National Library of Medicine. Gelsolin. Medical Subject Headings (MeSH). 2026. Unique ID D018260. http://id.nlm.nih.gov/mesh/2026/D018260
  2. Gelsolin. In: Wikipedia. https://en.wikipedia.org/wiki/Plasma_gelsolin
  3. Gelsolin. In: Wikidata. https://www.wikidata.org/wiki/Q24741962