Chemicals and Drugs

Gasdermins

A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

1 entry terms
  • Cancer Associated Gasdermin-Domain Containing (GSDMDC) Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2023

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.353
  2. D12.776w.543w.550w.450w.464
  3. D12.776w.543w.585w.400w.464

AMA Style

References

  1. National Library of Medicine. Gasdermins. Medical Subject Headings (MeSH). 2026. Unique ID D000094524. http://id.nlm.nih.gov/mesh/2026/D000094524
  2. Gasdermins. In: Wikidata. https://www.wikidata.org/wiki/Q24769482