Structured Summary
Abstract
A GAP JUNCTION beta subunit containing four transmembrane domains expressed in myelinating SCHWANN CELLS and is localized to peripheral MYELIN (e.g., noncompact myelin in the paranode and Schmitt-Lanterman incisures). Mutations in the human gene GJB1 are associated with X-linked CHARCOT-MARIE-TOOTH DISEASE type 1 (CMT1X).
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Classification
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Synonyms
10 entry terms
- Connexin 32
- Connexin 32 Protein
- Cx32 Protein
- GJB1 Protein
- Gap Junction B1
- Gap Junction beta1 Protein
- Gap Junction beta 1 Protein
- Protein, Connexin 32
- Protein, Cx32
- Protein, GJB1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2024(1993)
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AMA Style
References
- National Library of Medicine. Gap Junction beta-1 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000097002. http://id.nlm.nih.gov/mesh/2026/D000097002
- Gap Junction beta-1 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24783616