Chemicals and Drugs

Galantamine

A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A benzazepine derived from norbelladine. It is found in GALANTHUS and other AMARYLLIDACEAE. It is a cholinesterase inhibitor that has been used to reverse the muscular effects of GALLAMINE TRIETHIODIDE and TUBOCURARINE and has been studied as a treatment for ALZHEIMER DISEASE and other central nervous system disorders.

Chemical Identity

Chemical Information

Molecular Formula
C17H21NO3
Molecular Weight
287.35 g/mol
CAS Registry No.
357-70-0
IUPAC Name
(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
InChIKey
ASUTZQLVASHGKV-JDFRZJQESA-N
SMILES
CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O
MeSH Unique ID
D005702
Source
PubChem CID 9651

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Galantamin
  • Galanthamine
  • Lycoremine
  • Galanthamine Hydrobromide
  • Nivalin
  • Nivaline
  • Razadyne
  • Reminyl

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2004(1999)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.052.500w
  2. D03w.633.100.079.525w

MeSH Record

NLM Classification

QV 124

AMA Style

References

  1. National Library of Medicine. Galantamine. Medical Subject Headings (MeSH). 2026. Unique ID D005702. http://id.nlm.nih.gov/mesh/2026/D005702
  2. Galantamine. In: Wikipedia. https://en.wikipedia.org/wiki/Galantamine
  3. Galantamine. In: Wikidata. https://www.wikidata.org/wiki/Q412690
  4. Galantamine. In: PubChem Compound. CID 9651. https://pubchem.ncbi.nlm.nih.gov/compound/9651