Chemicals and Drugs

G(M3) Ganglioside

A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.

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Classification

Broader headings

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MeSH Record

Synonyms

7 entry terms
  • Ganglioside GM3
  • Hematoside
  • II3NeuAcLacCer
  • Sialyl Lactosylceramide
  • Sialyllactosylceramide
  • GM3, Ganglioside
  • Lactosylceramide, Sialyl

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

G(M3) gangliosidosis: coord NIM with GANGLIOSIDOSIS (IM)

MeSH Record

History Note

91(77); was see under GANGLIOSIDES 1977-90

MeSH Record

Previous Indexing

  • Gangliosides (1966-1976)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. G(M3) Ganglioside. Medical Subject Headings (MeSH). 2026. Unique ID D005679. http://id.nlm.nih.gov/mesh/2026/D005679
  2. G(M3) Ganglioside. In: Wikipedia. https://en.wikipedia.org/wiki/GM3
  3. G(M3) Ganglioside. In: Wikidata. https://www.wikidata.org/wiki/Q2782222