Diseases

Frasier Syndrome

A syndrome characterized by CHRONIC KIDNEY FAILURE and GONADAL DYSGENESIS in phenotypic females with karyotype of 46,XY or female individual with a normal 46,XX karyotype. It is caused by donor splice-site mutations of Wilms tumor suppressor gene (GENES, WILMS TUMOR) on chromosome 11.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome characterized by CHRONIC KIDNEY FAILURE and GONADAL DYSGENESIS in phenotypic females with karyotype of 46,XY or female individual with a normal 46,XX karyotype. It is caused by donor splice-site mutations of Wilms tumor suppressor gene (GENES, WILMS TUMOR) on chromosome 11.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

1 entry terms
  • Syndrome, Frasier

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

do not confuse with FRASER SYNDROME

MeSH Record

History Note

2006; use DENYS-DRASH SYNDROME 2002-2005

MeSH Hierarchy

Tree Numbers

  1. C12.050.351.875w.253w.096w.624w
  2. C12.050.351.968w.419w.780w.750w.500.500w
  3. C12.200.706w.316w.096w.624w
  4. C12.200.777w.419w.780w.750w.500.500w
  5. C12.800w.316w.096w.624w
  6. C12.950w.419w.780w.750w.500.500w
  7. C16w.131w.939w.316w.096w.624w
  8. C16w.320w.306w
  9. C19w.391.119w.096w.624w
  10. C23.550.291.500w.906w.500.500w

AMA Style

References

  1. National Library of Medicine. Frasier Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D052159. http://id.nlm.nih.gov/mesh/2026/D052159
  2. Frasier Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Frasier_syndrome
  3. Frasier Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q5493754