Structured Summary
Abstract
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously.
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Broader headings
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Synonyms
22 entry terms
- Frame Shift Mutation
- Mutation, Frameshift
- Out-of-Frame Mutation
- Frame Shift Mutations
- Frameshift Mutations
- Mutation, Frame Shift
- Mutation, Out-of-Frame
- Mutations, Frame Shift
- Mutations, Frameshift
- Mutations, Out-of-Frame
- Out of Frame Mutation
- Out-of-Frame Mutations
- Out-of-Frame Deletion
- Out-of-Frame Insertion
- Deletion, Out-of-Frame
- Deletions, Out-of-Frame
- Insertion, Out-of-Frame
- Insertions, Out-of-Frame
- Out of Frame Deletion
- Out of Frame Insertion
- Out-of-Frame Deletions
- Out-of-Frame Insertions
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Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
MeSH Record
Indexing Annotation
do not confuse with FRAMESHIFTING, RIBOSOMAL, physiology process & form of genetic translation; do not confuse effects of drug & radiation on frameshift mutation with drug- & radiation-induced frameshift mutation
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History Note
91
MeSH Record
Previous Indexing
- Mutation (1968-1990)
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AMA Style
References
- National Library of Medicine. Frameshift Mutation. Medical Subject Headings (MeSH). 2026. Unique ID D016368. http://id.nlm.nih.gov/mesh/2026/D016368
- Frameshift Mutation. In: Wikipedia. https://en.wikipedia.org/wiki/Frameshift_mutation
- Frameshift Mutation. In: Wikidata. https://www.wikidata.org/wiki/Q1440688