Chemicals and Drugs

Foscarnet

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.

Chemical Identity

Chemical Information

Molecular Formula
CH3O5P
Molecular Weight
126.01 g/mol
CAS Registry No.
4428-95-9
IUPAC Name
phosphonoformic acid
InChIKey
ZJAOAACCNHFJAH-UHFFFAOYSA-N
SMILES
C(=O)(O)P(=O)(O)O
MeSH Unique ID
D017245
Source
PubChem CID 3415

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Phosphonoformic Acid
  • Foscarnet Barium (2:3) Salt
  • Foscarnet Calcium (2:3) Salt
  • Foscarnet Disodium Salt
  • Foscarnet Magnesium (2:3) Salt
  • Foscarnet Manganese (2+) (2:3) Salt
  • Foscarnet Sodium
  • Foscarnet Sodium Hexahydrate
  • Foscarnet Trilithium Salt
  • Foscarnet Tripotassium Salt
  • Foscarnet Trisodium Salt
  • Foscavir
  • Phosphonoformate
  • Trisodium Phosphonoformate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1993 (1980); FOSCARNET was SY to PHOSPHONOFORMIC ACID (NM) 1983-1992

MeSH Record

Previous Indexing

  • Formates (1978-1980)
  • Organophosphorus Compounds (1978-1980)
  • Phosphonoacetic Acid (1981-1992)

MeSH Hierarchy

Tree Numbers

  1. D02w.241w.081.018w.677.250w
  2. D02w.705w.429.875.500w

AMA Style

References

  1. National Library of Medicine. Foscarnet. Medical Subject Headings (MeSH). 2026. Unique ID D017245. http://id.nlm.nih.gov/mesh/2026/D017245
  2. Foscarnet. In: Wikipedia. https://en.wikipedia.org/wiki/Foscarnet
  3. Foscarnet. In: Wikidata. https://www.wikidata.org/wiki/Q420387
  4. Foscarnet. In: PubChem Compound. CID 3415. https://pubchem.ncbi.nlm.nih.gov/compound/3415