Chemicals and Drugs

Fondaparinux

Synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery.

Chemical Identity

Chemical Information

Molecular Formula
C31H53N3O49S8
Molecular Weight
1508.3 g/mol
CAS Registry No.
104993-28-4
IUPAC Name
(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5R,6R)-6-[(2R,3S,4S,5R,6R)-2-carboxy-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-5-sulfooxyoxan-3-yl]oxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxy-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfoamino)-6-(sulfooxymethyl)oxan-2-yl]oxy-4,5-dihydroxyoxane-2-carboxylic acid
InChIKey
KANJSNBRCNMZMV-ABRZTLGGSA-N
SMILES
CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)O)O)O)NS(=O)(=O)O)O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O)NS(=O)(=O)O
MeSH Unique ID
D000077425
Source
PubChem CID 5282448

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Arixtra
  • Fondaparinux Sodium
  • Quixidar

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (2001)

MeSH Hierarchy

Tree Number

  1. D09w.698w.629w.429w

AMA Style

References

  1. National Library of Medicine. Fondaparinux. Medical Subject Headings (MeSH). 2026. Unique ID D000077425. http://id.nlm.nih.gov/mesh/2026/D000077425
  2. Fondaparinux. In: Wikipedia. https://en.wikipedia.org/wiki/Fondaparinux
  3. Fondaparinux. In: Wikidata. https://www.wikidata.org/wiki/Q27077698
  4. Fondaparinux. In: PubChem Compound. CID 5282448. https://pubchem.ncbi.nlm.nih.gov/compound/5282448