Structured Summary
Abstract
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
Chemical Identity
Chemical Information
- Molecular Formula
- C17H18F3NO
- Molecular Weight
- 309.33 g/mol
- CAS Registry No.
- 54910-89-3
- IUPAC Name
- N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
- InChIKey
- RTHCYVBBDHJXIQ-UHFFFAOYSA-N
- SMILES
- CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F
- MeSH Unique ID
- D005473
- Source
- PubChem CID 3386
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Fluoxetin
- N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
- Fluoxetine Hydrochloride
- Lilly-110140
- Prozac
- Sarafem
- Lilly 110140
- Lilly110140
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
90(79); was FLUOXETIN see under PROPYLAMINES 1979-88; was FLUOXETIN 1989
MeSH Record
Previous Indexing
- Phenyl Ethers (1974-1978)
- Propylamines (1966-1978)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Fluoxetine. Medical Subject Headings (MeSH). 2026. Unique ID D005473. http://id.nlm.nih.gov/mesh/2026/D005473
- Fluoxetine. In: Wikipedia. https://en.wikipedia.org/wiki/Fluoxetine
- Fluoxetine. In: Wikidata. https://www.wikidata.org/wiki/Q422244
- Fluoxetine. In: PubChem Compound. CID 3386. https://pubchem.ncbi.nlm.nih.gov/compound/3386