Structured Summary
Abstract
5-Fluoro-2'-deoxyuridylate. An inhibitor of thymidylate synthetase. Formed from 5-fluorouracil or 5-fluorodeoxyuridine.
Chemical Identity
Chemical Information
- Molecular Formula
- C9H12FN2O8P
- Molecular Weight
- 326.17 g/mol
- CAS Registry No.
- 134-46-3
- IUPAC Name
- [(2R,3S,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
- InChIKey
- HFEKDTCAMMOLQP-RRKCRQDMSA-N
- SMILES
- C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)COP(=O)(O)O)O
- MeSH Unique ID
- D005468
- Source
- PubChem CID 8642
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
3 entry terms
- 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
- FdUMP
- 5 Fluoro 2' Deoxyuridine 5' Monophosphate
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under DEOXYURACIL NUCLEOTIDES 1978-90; was see under URACIL NUCLEOTIDES 1975-77
MeSH Record
Previous Indexing
- Deoxyribonucleotides (1973-1974)
- Fluorine (1972-1974)
- Uracil Nucleotides (1972-1974)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Fluorodeoxyuridylate. Medical Subject Headings (MeSH). 2026. Unique ID D005468. http://id.nlm.nih.gov/mesh/2026/D005468
- Fluorodeoxyuridylate. In: Wikipedia. https://en.wikipedia.org/wiki/Fluorodeoxyuridylate
- Fluorodeoxyuridylate. In: Wikidata. https://www.wikidata.org/wiki/Q27105559
- Fluorodeoxyuridylate. In: PubChem Compound. CID 8642. https://pubchem.ncbi.nlm.nih.gov/compound/8642