Structured Summary
Abstract
A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Chemical Identity
Chemical Information
- Molecular Formula
- C24H30F2O6
- Molecular Weight
- 452.5 g/mol
- CAS Registry No.
- 67-73-2
- IUPAC Name
- (1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
- InChIKey
- FEBLZLNTKCEFIT-VSXGLTOVSA-N
- SMILES
- C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@@]53C)F)F)O
- MeSH Unique ID
- D005446
- Source
- PubChem CID 6215
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
25 entry terms
- Fluortriamcinolone Acetonide
- Acetonide, Fluocinolone
- Acetonide, Fluortriamcinolone
- Alvadermo
- Capex
- Co-Fluocin
- Cortiespec
- Derma-Smooth FS
- Flucinar
- Fluocid
- Fluodermo
- Fluonid
- Fluotrex
- Flurosyn
- Flusolgen
- Gelidina
- Jellin
- Jellisoft
- Synalar
- Synalar-HP
- Synamol
- Synemol
- Co Fluocin
- Derma Smooth FS
- Synalar HP
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
65(63)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Fluocinolone Acetonide. Medical Subject Headings (MeSH). 2026. Unique ID D005446. http://id.nlm.nih.gov/mesh/2026/D005446
- Fluocinolone Acetonide. In: Wikipedia. https://en.wikipedia.org/wiki/Fluocinolone_acetonide
- Fluocinolone Acetonide. In: Wikidata. https://www.wikidata.org/wiki/Q924467
- Fluocinolone Acetonide. In: PubChem Compound. CID 6215. https://pubchem.ncbi.nlm.nih.gov/compound/6215