Structured Summary
Abstract
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
Chemical Identity
Chemical Information
- Molecular Formula
- C15H14FN3O3
- Molecular Weight
- 303.29 g/mol
- CAS Registry No.
- 78755-81-4
- IUPAC Name
- ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- InChIKey
- OFBIFZUFASYYRE-UHFFFAOYSA-N
- SMILES
- CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C
- MeSH Unique ID
- D005442
- Source
- PubChem CID 3373
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- Flumazepil
- Anexate
- Lanexat
- Ro 15-1788
- Romazicon
- Ro 15 1788
- Ro 151788
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91; was FLUMAZEPIL 1987-90
MeSH Record
Previous Indexing
- Azepines (1966-1973)
- Benzodiazepinones (1974-1986)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QV 77.9
AMA Style
References
- National Library of Medicine. Flumazenil. Medical Subject Headings (MeSH). 2026. Unique ID D005442. http://id.nlm.nih.gov/mesh/2026/D005442
- Flumazenil. In: Wikipedia. https://en.wikipedia.org/wiki/Flumazenil
- Flumazenil. In: Wikidata. https://www.wikidata.org/wiki/Q421920
- Flumazenil. In: PubChem Compound. CID 3373. https://pubchem.ncbi.nlm.nih.gov/compound/3373