Chemicals and Drugs

Fibroblast Growth Factor Type 1 Receptor

A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fibroblast growth factor receptor with specificity for FIBROBLAST GROWTH FACTORS; HEPARAN SULFATE PROTEOGLYCAN; and NEURONAL CELL ADHESION MOLECULES. Several variants of the receptor exist due to multiple ALTERNATIVE SPLICING of its mRNA. Fibroblast growth factor receptor 1 contains three extracellular IMMUNOGLOBULIN C2-SET DOMAINS and is a tyrosine kinase that transmits signals through the MAP KINASE SIGNALING SYSTEM.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

9 entry terms
  • CD331 Antigen
  • FGFR1 Protein
  • FGFR1 Tyrosine Kinase
  • Fibroblast Growth Factor Receptor 1
  • Receptor, Fibroblast Growth Factor, Type 1
  • fms-Like Tyrosine Kinase-2
  • Antigen, CD331
  • fms Like Tyrosine Kinase 2
  • Fibroblast Growth Factor Soluble Receptor 1

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2006(1992)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.400w.177
  2. D12.776w.476.568w.400w.177
  3. D12.776w.543w.750w.630w.440
  4. D12.776w.543w.750w.750w.400w.370w.500

AMA Style

References

  1. National Library of Medicine. Fibroblast Growth Factor Type 1 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D051496. http://id.nlm.nih.gov/mesh/2026/D051496
  2. Fibroblast Growth Factor Type 1 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q5446453