Structured Summary
Abstract
A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
12 entry terms
- DL-3-(4-Chlorophenyl)alanine
- Fenclonin
- p-Chlorophenylalanine
- para-Chlorophenylalanine
- para Chlorophenylalanine
- CP-10,188
- Fenclonine (L)-Isomer
- Fenclonine Hydrobromide
- Fenclonine Hydrochloride
- Fenclonine, (D)-Isomer
- Hydrobromide, Fenclonine
- Hydrochloride, Fenclonine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
93(71)
MeSH Record
Previous Indexing
- Phenylalanine (1966-1970)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Fenclonine. Medical Subject Headings (MeSH). 2026. Unique ID D010134. http://id.nlm.nih.gov/mesh/2026/D010134
- Fenclonine. In: Wikipedia. https://en.wikipedia.org/wiki/Fenclonine
- Fenclonine. In: Wikidata. https://www.wikidata.org/wiki/Q5443204