Chemicals and Drugs

Felodipine

A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.

Chemical Identity

Chemical Information

Molecular Formula
C18H19Cl2NO4
Molecular Weight
384.2 g/mol
CAS Registry No.
72509-76-3
IUPAC Name
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
RZTAMFZIAATZDJ-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
MeSH Unique ID
D015736
Source
PubChem CID 3333

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

30 entry terms
  • Agon
  • Felo Biochemie
  • Felo-Puren
  • Felobeta
  • Felocor
  • Felodipin 1A Pharma
  • Felodipin AL
  • Felodipin AZU
  • Felodipin AbZ
  • Felodipin Dura
  • Felodipin Heumann
  • Felodipin Stada
  • Felodipin Von Ct
  • Felodipin-Ratiopharm
  • Felodur
  • Felogamma
  • Fensel
  • Flodil
  • H 154-82
  • Modip
  • Munobal
  • Perfudal
  • Plendil
  • Renedil
  • Felo Puren
  • Felodipin Ratiopharm
  • H 154 82
  • H 15482
  • Heumann, Felodipin
  • Von Ct, Felodipin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Nifedipine/analogs & derivatives (1981-1986)
  • Nitrendipine/analogs & derivatives (1987-1989)
  • Pyridines (1966-1980)

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.203.250w

AMA Style

References

  1. National Library of Medicine. Felodipine. Medical Subject Headings (MeSH). 2026. Unique ID D015736. http://id.nlm.nih.gov/mesh/2026/D015736
  2. Felodipine. In: Wikipedia. https://en.wikipedia.org/wiki/Felodipine
  3. Felodipine. In: Wikidata. https://www.wikidata.org/wiki/Q420644
  4. Felodipine. In: PubChem Compound. CID 3333. https://pubchem.ncbi.nlm.nih.gov/compound/3333