Structured Summary
Abstract
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
12 entry terms
- Antigens, CD178
- CD178 Antigen
- CD178 Antigens
- CD95 Antigen Ligand
- CD95 Ligand
- CD95L
- Fas Ligand
- Fas Ligand (FasL)
- FasL Protein
- TNF Superfamily, Member 6
- Tumor Necrosis Factor Ligand Superfamily Member 6
- Antigen, CD178
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1994)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Fas Ligand Protein. Medical Subject Headings (MeSH). 2026. Unique ID D053222. http://id.nlm.nih.gov/mesh/2026/D053222
- Fas Ligand Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24739308