Structured Summary
Abstract
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
MeSH Record
Classification
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MeSH Record
Synonyms
10 entry terms
- FADD Protein, Fas-Associating
- Fas Associated Death Domain Protein
- Fas-Associating Protein FADD
- Fas-Associating Protein with Death Domain
- MORT1 Protein
- FADD Protein, Fas Associating
- FADD, Fas-Associating Protein
- Fas Associating Protein FADD
- Fas Associating Protein with Death Domain
- Fas-Associating FADD Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1995)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Fas-Associated Death Domain Protein. Medical Subject Headings (MeSH). 2026. Unique ID D053200. http://id.nlm.nih.gov/mesh/2026/D053200
- Fas-Associated Death Domain Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24771396