Diseases

Familial Dysalbuminemic Hyperthyroxinemia

An inherited autosomal dominant trait characterized by abnormally elevated levels of total serum THYROXINE; (T4) in euthyroid patients with abnormal SERUM ALBUMIN that binds T4 with enhanced affinity. The serum levels of free T4, free T3, and TSH are normal. It is one of several T4 abnormalities produced by non-thyroid disorder. This condition is due to mutations of the ALB gene on CHROMOSOME 4.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inherited autosomal dominant trait characterized by abnormally elevated levels of total serum THYROXINE; (T4) in euthyroid patients with abnormal SERUM ALBUMIN that binds T4 with enhanced affinity. The serum levels of free T4, free T3, and TSH are normal. It is one of several T4 abnormalities produced by non-thyroid disorder. This condition is due to mutations of the ALB gene on CHROMOSOME 4.

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Synonyms

2 entry terms
  • Hyperthyroxinemia, Familial Dysalbuminemic
  • Dysalbuminemic Hyperthyroxinemia, Familial

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2006

MeSH Record

Previous Indexing

  • Serum Albumin (1982-2005)
  • Thyroxine (1982-2005)

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References

  1. National Library of Medicine. Familial Dysalbuminemic Hyperthyroxinemia. Medical Subject Headings (MeSH). 2026. Unique ID D050010. http://id.nlm.nih.gov/mesh/2026/D050010
  2. Familial Dysalbuminemic Hyperthyroxinemia. In: Wikipedia. https://en.wikipedia.org/wiki/Familial_dysalbuminemic_hyperthyroxinemia
  3. Familial Dysalbuminemic Hyperthyroxinemia. In: Wikidata. https://www.wikidata.org/wiki/Q5432934