Chemicals and Drugs

Famciclovir

An aminopurine derivative and prodrug of penciclovir which is a competitive inhibitor of herpes simplex 2 DNA polymerase. It is used to treat HERPES SIMPLEX VIRUS INFECTION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An aminopurine derivative and prodrug of penciclovir which is a competitive inhibitor of herpes simplex 2 DNA polymerase. It is used to treat HERPES SIMPLEX VIRUS INFECTION.

Chemical Identity

Chemical Information

Molecular Formula
C14H19N5O4
Molecular Weight
321.33 g/mol
CAS Registry No.
104227-87-4
IUPAC Name
[2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate
InChIKey
GGXKWVWZWMLJEH-UHFFFAOYSA-N
SMILES
CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
MeSH Unique ID
D000077595
Source
PubChem CID 3324

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester)
  • 9-(4-Acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine
  • BRL 42810
  • BRL-42810
  • Famvir
  • BRL42810

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1989)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Famciclovir. Medical Subject Headings (MeSH). 2026. Unique ID D000077595. http://id.nlm.nih.gov/mesh/2026/D000077595
  2. Famciclovir. In: Wikipedia. https://en.wikipedia.org/wiki/Famciclovir
  3. Famciclovir. In: Wikidata. https://www.wikidata.org/wiki/Q420186
  4. Famciclovir. In: PubChem Compound. CID 3324. https://pubchem.ncbi.nlm.nih.gov/compound/3324