Chemicals and Drugs

Factor XIII

A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.

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Classification

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Synonyms

13 entry terms
  • Blood Coagulation Factor XIII
  • Coagulation Factor XIII
  • Factor 13
  • Factor Thirteen
  • Factor XIII Transamidase
  • Fibrin Stabilizing Factor
  • Fibrinase
  • Laki Lorand Factor
  • Laki-Lorand Factor
  • Factor XIII, Coagulation
  • Stabilizing Factor, Fibrin
  • Transamidase, Factor XIII
  • XIII, Coagulation Factor

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

activated form use FACTOR XIIIA

MeSH Record

History Note

1970(1964); for FACTOR XIII TRANSAMIDASE see TRANSGLUTAMINASES (1990-2001)

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References

  1. National Library of Medicine. Factor XIII. Medical Subject Headings (MeSH). 2026. Unique ID D005176. http://id.nlm.nih.gov/mesh/2026/D005176
  2. Factor XIII. In: Wikipedia. https://en.wikipedia.org/wiki/Factor_XIII
  3. Factor XIII. In: Wikidata. https://www.wikidata.org/wiki/Q423712