Chemicals and Drugs

Factor V

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.

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Synonyms

8 entry terms
  • AC Globulin
  • Blood Coagulation Factor V
  • Coagulation Factor V
  • Factor 5
  • Factor Five
  • Factor Pi
  • Proaccelerin
  • Factor V, Coagulation

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.125.300w
  2. D12.776w.811w.272w
  3. D23.119.300w

AMA Style

References

  1. National Library of Medicine. Factor V. Medical Subject Headings (MeSH). 2026. Unique ID D005165. http://id.nlm.nih.gov/mesh/2026/D005165
  2. Factor V. In: Wikipedia. https://en.wikipedia.org/wiki/Factor_V
  3. Factor V. In: Wikidata. https://www.wikidata.org/wiki/Q422831