Chemicals and Drugs

Factor IX

Storage-stable blood coagulation factor acting in the intrinsic pathway of blood coagulation. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Storage-stable blood coagulation factor acting in the intrinsic pathway of blood coagulation. Its activated form, IXa, forms a complex with factor VIII and calcium on platelet factor 3 to activate factor X to Xa. Deficiency of factor IX results in HEMOPHILIA B (Christmas Disease).

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Synonyms

10 entry terms
  • Autoprothrombin II
  • Blood Coagulation Factor IX
  • Christmas Factor
  • Coagulation Factor IX
  • Factor 9
  • Factor IX Complex
  • Factor IX Fraction
  • Factor Nine
  • Plasma Thromboplastin Component
  • Factor IX, Coagulation

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Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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References

  1. National Library of Medicine. Factor IX. Medical Subject Headings (MeSH). 2026. Unique ID D005164. http://id.nlm.nih.gov/mesh/2026/D005164
  2. Factor IX. In: Wikidata. https://www.wikidata.org/wiki/Q32855876