Chemicals and Drugs

Ezrin

A cytoskeletal protein and PROTEIN-TYROSINE KINASE substrate that links cytoskeletal structures to the PLASMA MEMBRANE. In EPITHELIAL CELLS, it is essential for the formation of MICROVILLI and membrane ruffles on the apical pole and is also required for macropinocytosis (see PINOCYTOSIS) along with the GUANINE NUCLEOTIDE EXCHANGE FACTOR PLEKHG6.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cytoskeletal protein and PROTEIN-TYROSINE KINASE substrate that links cytoskeletal structures to the PLASMA MEMBRANE. In EPITHELIAL CELLS, it is essential for the formation of MICROVILLI and membrane ruffles on the apical pole and is also required for macropinocytosis (see PINOCYTOSIS) along with the GUANINE NUCLEOTIDE EXCHANGE FACTOR PLEKHG6.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • EZR Protein
  • Phosphoprotein p81
  • Villin-2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1986)

MeSH Hierarchy

Tree Number

  1. D12.776w.220.419

AMA Style

References

  1. National Library of Medicine. Ezrin. Medical Subject Headings (MeSH). 2026. Unique ID D000099149. http://id.nlm.nih.gov/mesh/2026/D000099149
  2. Ezrin. In: Wikidata. https://www.wikidata.org/wiki/Q22679669