Diseases

Extramammary Paget Disease

A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

17 entry terms
  • Extra-Mammary Paget Disease
  • Extra-Mammary Paget's Disease
  • Extramammary Paget's Disease
  • Paget Disease Extramammary
  • Paget Disease, Extra-Mammary
  • Paget Disease, Extramammary
  • Paget's Disease, Extra-Mammary
  • Paget's Disease, Extramammary
  • Extra Mammary Paget Disease
  • Extra Mammary Paget's Disease
  • Extra-Mammary Pagets Disease
  • Extramammary Pagets Disease
  • Extramammary, Paget Disease
  • Paget Disease, Extra Mammary
  • Paget's Disease, Extra Mammary
  • Pagets Disease, Extra-Mammary
  • Pagets Disease, Extramammary

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

neoplastic; coordinate with precoordinated organ/neoplasm term

MeSH Record

History Note

2010(1963)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.470.200w.025w.660w
  2. C04w.557.470.615.660w

AMA Style

References

  1. National Library of Medicine. Extramammary Paget Disease. Medical Subject Headings (MeSH). 2026. Unique ID D010145. http://id.nlm.nih.gov/mesh/2026/D010145
  2. Extramammary Paget Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Extramammary_Paget%27s_disease
  3. Extramammary Paget Disease. In: Wikidata. https://www.wikidata.org/wiki/Q3077016