Chemicals and Drugs

Exfoliatins

Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative disease, toxic epidermal necrolysis, etc.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative disease, toxic epidermal necrolysis, etc.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Epidermolysins
  • Staphylococcal Exfoliative Toxin
  • Exfoliative Toxin, Staphylococcal
  • Toxin, Staphylococcal Exfoliative
  • Dermolysins
  • Epidermolytic Toxins
  • Exfoliatin Toxin A
  • Exfoliative Toxin B
  • Exfoliative Toxins
  • Toxin A, Exfoliatin
  • Toxin B, Exfoliative
  • Toxins, Epidermolytic
  • Toxins, Exfoliative

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/antag permitted but consider also ANTITOXINS

MeSH Record

History Note

91(78); was see under BACTERIAL TOXINS 1978-90

MeSH Record

Previous Indexing

  • Bacterial Proteins (1966-1976)
  • Bacterial Toxins (1977)
  • Staphylococcal Infections (1966-1977)
  • Toxins (1966-1976)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Exfoliatins. Medical Subject Headings (MeSH). 2026. Unique ID D005083. http://id.nlm.nih.gov/mesh/2026/D005083
  2. Exfoliatins. In: Wikipedia. https://en.wikipedia.org/wiki/Exfoliatin
  3. Exfoliatins. In: Wikidata. https://www.wikidata.org/wiki/Q1383734