Chemicals and Drugs

Eukaryotic Initiation Factor-4A

A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

27 entry terms
  • EIF-4A
  • Eukaryotic Initiation Factor EIF-4A
  • Eukaryotic Peptide Initiation Factor-4A
  • Peptide Initiation Factor EIF-4A
  • Eukaryotic Initiation Factor 4A
  • Eukaryotic Initiation Factor EIF 4A
  • Eukaryotic Peptide Initiation Factor 4A
  • Initiation Factor-4A, Eukaryotic
  • Peptide Initiation Factor EIF 4A
  • EIF-4A1
  • EIF-4A2
  • EIF-4A3
  • EIF4AIII
  • Eukaryotic Initiation Factor-4A1
  • Eukaryotic Initiation Factor-4A2
  • Eukaryotic Initiation Factor-4A3
  • Eukaryotic Translation-Initiation Factor 4AIII
  • Eukaryotic Initiation Factor 4A1
  • Eukaryotic Initiation Factor 4A2
  • Eukaryotic Initiation Factor 4A3
  • Eukaryotic Translation Initiation Factor 4AIII
  • Factor-4A1, Eukaryotic Initiation
  • Factor-4A2, Eukaryotic Initiation
  • Factor-4A3, Eukaryotic Initiation
  • Initiation Factor-4A1, Eukaryotic
  • Initiation Factor-4A2, Eukaryotic
  • Initiation Factor-4A3, Eukaryotic

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; use EUKARYOTIC INITIATION FACTOR-F4A (NM) 1980-2001

MeSH Record

Previous Indexing

  • Peptide Initiation Factors (1980-2002)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.445w.735.720w.500w
  2. D12.776w.835w.725w.868w.500w.500w

AMA Style

References

  1. National Library of Medicine. Eukaryotic Initiation Factor-4A. Medical Subject Headings (MeSH). 2026. Unique ID D039601. http://id.nlm.nih.gov/mesh/2026/D039601
  2. Eukaryotic Initiation Factor-4A. In: Wikipedia. https://en.wikipedia.org/wiki/EIF4A
  3. Eukaryotic Initiation Factor-4A. In: Wikidata. https://www.wikidata.org/wiki/Q5323174