Chemicals and Drugs

Etretinate

An oral retinoid used in the treatment of keratotic genodermatosis, lichen planus, and psoriasis. Beneficial effects have also been claimed in the prophylaxis of epithelial neoplasia. The compound may be teratogenic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oral retinoid used in the treatment of keratotic genodermatosis, lichen planus, and psoriasis. Beneficial effects have also been claimed in the prophylaxis of epithelial neoplasia. The compound may be teratogenic.

Chemical Identity

Chemical Information

Molecular Formula
C23H30O3
Molecular Weight
354.5 g/mol
CAS Registry No.
54350-48-0
IUPAC Name
ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
InChIKey
HQMNCQVAMBCHCO-DJRRULDNSA-N
SMILES
CCOC(=O)/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C(=C(C=C1C)OC)C)C
MeSH Unique ID
D005050
Source
PubChem CID 5282375

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Ethyl Etrinoate
  • Etrinoate, Ethyl
  • B10-9359
  • Ro 10-9359
  • Ro-10-9359
  • Tigason
  • Tigazon
  • B10 9359
  • B109359
  • Ro 10 9359
  • Ro 109359
  • Ro109359

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1984(1980); was RO 10-9359 see under TRETINOIN 1980-1983

MeSH Record

Previous Indexing

  • Tretinoin/analogs & derivatives (1975-1979)
  • Vitamin A (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.455w.326.271w.665w.202w.495w.250w
  2. D02w.455w.849w.131w.495w.250w
  3. D23.767w.261w.700w.250w

AMA Style

References

  1. National Library of Medicine. Etretinate. Medical Subject Headings (MeSH). 2026. Unique ID D005050. http://id.nlm.nih.gov/mesh/2026/D005050
  2. Etretinate. In: Wikipedia. https://en.wikipedia.org/wiki/Etretinate
  3. Etretinate. In: Wikidata. https://www.wikidata.org/wiki/Q554297
  4. Etretinate. In: PubChem Compound. CID 5282375. https://pubchem.ncbi.nlm.nih.gov/compound/5282375