Chemicals and Drugs

Etoricoxib

A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.

Chemical Identity

Chemical Information

Molecular Formula
C18H15ClN2O2S
Molecular Weight
358.8 g/mol
CAS Registry No.
202409-33-4
IUPAC Name
5-chloro-2-(6-methyl-3-pyridinyl)-3-(4-methylsulfonylphenyl)pyridine
InChIKey
MNJVRJDLRVPLFE-UHFFFAOYSA-N
SMILES
CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C
MeSH Unique ID
D000077613
Source
PubChem CID 123619

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Arcoxia
  • L-791456
  • MK 0663
  • MK-0663
  • L 791456
  • L791456
  • MK0663

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (2001)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Etoricoxib. Medical Subject Headings (MeSH). 2026. Unique ID D000077613. http://id.nlm.nih.gov/mesh/2026/D000077613
  2. Etoricoxib. In: Wikipedia. https://en.wikipedia.org/wiki/Etoricoxib
  3. Etoricoxib. In: Wikidata. https://www.wikidata.org/wiki/Q631202
  4. Etoricoxib. In: PubChem Compound. CID 123619. https://pubchem.ncbi.nlm.nih.gov/compound/123619