Chemicals and Drugs

Etodolac

A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (POSTOPERATIVE PAIN).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (POSTOPERATIVE PAIN).

Chemical Identity

Chemical Information

Molecular Formula
C17H21NO3
Molecular Weight
287.35 g/mol
CAS Registry No.
41340-25-4
IUPAC Name
2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid
InChIKey
NNYBQONXHNTVIJ-UHFFFAOYSA-N
SMILES
CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O
MeSH Unique ID
D017308
Source
PubChem CID 3308

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Etodolic Acid
  • AY-24,236
  • AY-24236
  • Etodolac, (+-)-Isomer
  • Etodolac, (-)-Isomer
  • Etodolac, (S)-Isomer
  • Etodolac, Monosodium Salt
  • Etodolac, Monosodium Salt, (+-) Isomer
  • Etodolac, Monosodium Salt, (S)-Isomer
  • Lodine
  • Ramodar
  • Ultradol
  • AY 24,236
  • AY 24236

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1993 (1976)

MeSH Record

Previous Indexing

  • Acetic Acids (1976-1988)
  • Indoleacetic Acids (1976-1992)

MeSH Hierarchy

Tree Numbers

  1. D03w.066.288.200w
  2. D03w.633.100.473.404.200w

AMA Style

References

  1. National Library of Medicine. Etodolac. Medical Subject Headings (MeSH). 2026. Unique ID D017308. http://id.nlm.nih.gov/mesh/2026/D017308
  2. Etodolac. In: Wikipedia. https://en.wikipedia.org/wiki/Etodolac
  3. Etodolac. In: Wikidata. https://www.wikidata.org/wiki/Q2465218
  4. Etodolac. In: PubChem Compound. CID 3308. https://pubchem.ncbi.nlm.nih.gov/compound/3308