Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Erythrocyte Aggregation

The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.

MeSH Record

Classification

Broader headings

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See Also

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Synonyms

19 entry terms
  • Aggregation, Erythrocyte
  • Aggregations, Erythrocyte
  • Erythrocyte Aggregations
  • Agglutination, Intravascular
  • Erythrocyte Aggregation, Intravascular
  • Intravascular Agglutination
  • Intravascular Erythrocyte Aggregation
  • Rouleaux Formation, Erythrocyte
  • Agglutinations, Intravascular
  • Aggregation, Intravascular Erythrocyte
  • Aggregations, Intravascular Erythrocyte
  • Erythrocyte Aggregations, Intravascular
  • Erythrocyte Rouleaux Formation
  • Erythrocyte Rouleaux Formations
  • Formation, Erythrocyte Rouleaux
  • Formations, Erythrocyte Rouleaux
  • Intravascular Agglutinations
  • Intravascular Erythrocyte Aggregations
  • Rouleaux Formations, Erythrocyte

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

coordinate with disease /blood, not disease /physiopathol

MeSH Record

History Note

1976

MeSH Record

Previous Indexing

  • Erythrocytes (1966-1975)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.625.225w
  2. E05.200.625.225w
  3. G09.188.370w.187w

MeSH Record

NLM Classification

WH 150

AMA Style

References

  1. National Library of Medicine. Erythrocyte Aggregation. Medical Subject Headings (MeSH). 2026. Unique ID D004903. http://id.nlm.nih.gov/mesh/2026/D004903
  2. Erythrocyte Aggregation. In: Wikipedia. https://en.wikipedia.org/wiki/Erythrocyte_aggregation
  3. Erythrocyte Aggregation. In: Wikidata. https://www.wikidata.org/wiki/Q17119113