Structured Summary
Abstract
A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF RECEPTOR and the ERBB-2 RECEPTOR. Overexpression of the erbB-3 receptor is associated with TUMORIGENESIS.
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Synonyms
24 entry terms
- HER-3 Proto-Oncogene Protein
- Proto-Oncogene Protein c-erbB-3
- Proto-Oncogene Protein erbB-3
- Proto-Oncogene Proteins erbB-3
- Proto-oncogene-like Protein c-ErbB-2
- Receptor, ErbB-3
- Tyrosine Kinase-type Cell Surface Receptor HER3
- c-erbB-3 Protein
- erbB-3 Protein
- HER 3 Proto Oncogene Protein
- Protein c-ErbB-2, Proto-oncogene-like
- Proto Oncogene Protein c erbB 3
- Proto Oncogene Protein erbB 3
- Proto Oncogene Proteins erbB 3
- Proto oncogene like Protein c ErbB 2
- Proto-Oncogene Protein, HER-3
- Receptor, ErbB 3
- Tyrosine Kinase type Cell Surface Receptor HER3
- c erbB 3 Protein
- c-ErbB-2, Proto-oncogene-like Protein
- c-erbB-3, Proto-Oncogene Protein
- erbB 3 Protein
- erbB-3, Proto-Oncogene Protein
- erbB-3, Proto-Oncogene Proteins
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2000; use RECEPTOR, ERBB-3 (NM) 1990-1999
MeSH Record
Previous Indexing
- Proto-Oncogene Proteins (1993-1999)
- Receptor, Epidermal Growth Factor (1990-1999)
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AMA Style
References
- National Library of Medicine. ErbB-3 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D020893. http://id.nlm.nih.gov/mesh/2026/D020893
- ErbB-3 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21104746