Chemicals and Drugs

Epothilones

A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Epothilon
  • Epothilone

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2003

MeSH Record

Previous Indexing

  • Epoxy Compounds (1995-2002)
  • Macrolides (1998-2002)

MeSH Hierarchy

Tree Number

  1. D02w.540w.576w.500w.984w

AMA Style

References

  1. National Library of Medicine. Epothilones. Medical Subject Headings (MeSH). 2026. Unique ID D034261. http://id.nlm.nih.gov/mesh/2026/D034261
  2. Epothilones. In: Wikipedia. https://en.wikipedia.org/wiki/Epothilone
  3. Epothilones. In: Wikidata. https://www.wikidata.org/wiki/Q408201