Structured Summary
Abstract
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.
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Classification
Broader headings
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Synonyms
12 entry terms
- B61 Secreted Protein, Endothelium
- EFNA1
- EPLG1
- Eck Ligand
- Eck RPTK Ligand
- Endothelium Secreted Protein B61
- Epl1 Protein
- LERK-1 Protein
- Ephrin A1
- LERK 1 Protein
- Ligand, Eck
- RPTK Ligand, Eck
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; use EPHRIN-A1 (NM) 1990-2002
MeSH Record
Previous Indexing
- Proteins (1990-2002)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Ephrin-A1. Medical Subject Headings (MeSH). 2026. Unique ID D036382. http://id.nlm.nih.gov/mesh/2026/D036382
- Ephrin-A1. In: Wikidata. https://www.wikidata.org/wiki/Q21156333