Chemicals and Drugs

Eph Family Receptors

A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

15 entry terms
  • Eph Receptor Tyrosine Kinase
  • Eph Receptors
  • Ephrin Receptors
  • Receptors, Eph Family
  • Receptors, Eph
  • Receptors, Ephrin
  • EphA Receptors
  • EphB Receptor
  • EphB Receptors
  • Ephrin A Receptors
  • Ephrin B Receptor
  • Ephrin B Receptors
  • Receptor, Ephrin B
  • Receptors, EphB
  • Receptors, Ephrin A

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; use RECEPTORS, EPH FAMILY (NM) 1999-2002, for EPH RECEPTOR TYROSINE KINASE use EPHA1 RECEPTOR (NM) 1999-2002;

MeSH Record

Previous Indexing

  • Protein-Tyrosine Kinase (1988-1993)
  • Receptor Protein-Tyrosine Kinases (1994-2002)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.400w.850w
  2. D12.776w.476.568w.400w.850w
  3. D12.776w.543w.750w.630w.500w

AMA Style

References

  1. National Library of Medicine. Eph Family Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D036081. http://id.nlm.nih.gov/mesh/2026/D036081
  2. Eph Family Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Ephrin_receptor
  3. Eph Family Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q423602