Diseases

Eosinophilia-Myalgia Syndrome

A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

MeSH Record

Classification

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MeSH Record

See Also

MeSH Record

Synonyms

11 entry terms
  • Eosinophilia Myalgia Syndrome
  • Eosinophilia-Myalgia Syndromes
  • Syndrome, Eosinophilia-Myalgia
  • Syndromes, Eosinophilia-Myalgia
  • Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related
  • L-Tryptophan-Related Eosinophilia-Myalgia Syndrome
  • Syndrome, Eosinophilia-Myalgia, L-Tryptophan-Related
  • Eosinophilia-Myalgia Syndromes, L-Tryptophan-Related
  • L-Tryptophan-Related Eosinophilia-Myalgia Syndromes
  • Syndrome, L-Tryptophan-Related Eosinophilia-Myalgia
  • Syndromes, L-Tryptophan-Related Eosinophilia-Myalgia

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

92

MeSH Record

Previous Indexing

  • Eosinophilia/chemically induced (1989-1990)
  • Muscular Diseases/chemically induced (1990)
  • Tryptophan/adverse effects (1989-1990)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Eosinophilia-Myalgia Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D016603. http://id.nlm.nih.gov/mesh/2026/D016603
  2. Eosinophilia-Myalgia Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Eosinophilia%E2%80%93myalgia_syndrome
  3. Eosinophilia-Myalgia Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q3508806