Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Energy-Filtering Transmission Electron Microscopy

An analytical transmission electron microscopy method using an electron microscope fitted with an energy filtering lens. The method is based on the principle that some of the ELECTRONS passing through the specimen will lose energy when they ionize inner shell electrons of the atoms in the specimen. The amount of energy loss is dependent upon the element. Analysis of the energy loss spectrum (ELECTRON ENERGY-LOSS SPECTROSCOPY) reveals the elemental composition of a specimen. It is used analytically and quantitatively to determine which, how much of, and where specific ELEMENTS are in a sample. For example, it is used for elemental mapping of PHOSPHORUS to trace the strands of NUCLEIC ACIDS in nucleoprotein complexes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An analytical transmission electron microscopy method using an electron microscope fitted with an energy filtering lens. The method is based on the principle that some of the ELECTRONS passing through the specimen will lose energy when they ionize inner shell electrons of the atoms in the specimen. The amount of energy loss is dependent upon the element. Analysis of the energy loss spectrum (ELECTRON ENERGY-LOSS SPECTROSCOPY) reveals the elemental composition of a specimen. It is used analytically and quantitatively to determine which, how much of, and where specific ELEMENTS are in a sample. For example, it is used for elemental mapping of PHOSPHORUS to trace the strands of NUCLEIC ACIDS in nucleoprotein complexes.

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Classification

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Synonyms

13 entry terms
  • EF-TEM
  • EFTEM
  • Electron Spectroscopic Imaging
  • Energy-Filtered TEM
  • Energy-Filtered Transmission Electron Microscopy
  • Microscopy, Energy-Filtering Transmission Electron
  • Energy Filtered TEM
  • Energy Filtered Transmission Electron Microscopy
  • Energy Filtering Transmission Electron Microscopy
  • Imaging, Electron Spectroscopic
  • Microscopy, Energy Filtering Transmission Electron
  • Spectroscopic Imaging, Electron
  • TEM, Energy-Filtered

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Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

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History Note

2005

MeSH Record

Previous Indexing

  • Microscopy, Electron (1993-2004)

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References

  1. National Library of Medicine. Energy-Filtering Transmission Electron Microscopy. Medical Subject Headings (MeSH). 2026. Unique ID D046032. http://id.nlm.nih.gov/mesh/2026/D046032
  2. Energy-Filtering Transmission Electron Microscopy. In: Wikidata. https://www.wikidata.org/wiki/Q72392198