Chemicals and Drugs

Endothelium-Dependent Relaxing Factors

Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Paracrine substances produced by the VASCULAR ENDOTHELIUM with VASCULAR SMOOTH MUSCLE relaxation (VASODILATION) activities. Several factors have been identified, including NITRIC OXIDE and PROSTACYCLIN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

18 entry terms
  • Endothelium-Dependent Relaxing Factor
  • Endothelium-Dependent Vasodilators
  • Endothelium-Derived Relaxant Factor
  • Endothelium-Derived Relaxing Factor
  • Endothelium Dependent Relaxing Factor
  • Endothelium Dependent Relaxing Factors
  • Endothelium Dependent Vasodilators
  • Endothelium Derived Relaxant Factor
  • Endothelium Derived Relaxing Factor
  • Relaxant Factor, Endothelium-Derived
  • Relaxing Factor, Endothelium-Dependent
  • Relaxing Factor, Endothelium-Derived
  • Relaxing Factors, Endothelium-Dependent
  • Vasodilators, Endothelium-Dependent
  • Neutrophil-Derived Relaxant Factor
  • Factor, Neutrophil-Derived Relaxant
  • Neutrophil Derived Relaxant Factor
  • Relaxant Factor, Neutrophil-Derived

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2004; use NITRIC OXIDE 1990-2003

MeSH Record

Previous Indexing

  • Endothelium (1984-2003)
  • Nitric Oxide (1986-2003)
  • Vasodilator Agents (1984-2003)

MeSH Hierarchy

Tree Number

  1. D27.505.954.411w.918w.500

MeSH Record

NLM Classification

QV 150

AMA Style

References

  1. National Library of Medicine. Endothelium-Dependent Relaxing Factors. Medical Subject Headings (MeSH). 2026. Unique ID D045462. http://id.nlm.nih.gov/mesh/2026/D045462
  2. Endothelium-Dependent Relaxing Factors. In: Wikidata. https://www.wikidata.org/wiki/Q50430313