Chemicals and Drugs

Endosulfan

A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)

Chemical Identity

Chemical Information

Molecular Formula
C9H6Cl6O3S
Molecular Weight
406.9 g/mol
CAS Registry No.
115-29-7
IUPAC Name
1,9,10,11,12,12-hexachloro-4,6-dioxa-5lambda4-thiatricyclo[7.2.1.02,8]dodec-10-ene 5-oxide
InChIKey
RDYMFSUJUZBWLH-UHFFFAOYSA-N
SMILES
C1C2C(COS(=O)O1)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl
MeSH Unique ID
D004726
Source
PubChem CID 3224

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Thiodan
  • Thiodon
  • Thiotox
  • alpha-Endosulfan
  • beta-Endosulfan
  • alpha Endosulfan
  • beta Endosulfan

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(72)

MeSH Record

Previous Indexing

  • Insecticides (1966-1972)

MeSH Hierarchy

Tree Numbers

  1. D02w.886w.092.408w
  2. D03w.633.100.197.408w

AMA Style

References

  1. National Library of Medicine. Endosulfan. Medical Subject Headings (MeSH). 2026. Unique ID D004726. http://id.nlm.nih.gov/mesh/2026/D004726
  2. Endosulfan. In: Wikipedia. https://en.wikipedia.org/wiki/Endosulfan
  3. Endosulfan. In: Wikidata. https://www.wikidata.org/wiki/Q424208
  4. Endosulfan. In: PubChem Compound. CID 3224. https://pubchem.ncbi.nlm.nih.gov/compound/3224