Chemicals and Drugs

Endosomal Sorting Complexes Required for Transport

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.

MeSH Record

Classification

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MeSH Record

Synonyms

12 entry terms
  • ESCRT Complexes
  • ESCRT Machinery
  • Endosomal Sorting Complex Required for Transport
  • Endosomal Sorting Complex Required for Transport Machinery
  • Complexes, ESCRT
  • Machinery, ESCRT
  • ESCRT I
  • ESCRT II
  • ESCRT III
  • Endosomal Sorting Complex Required for Transport I
  • Endosomal Sorting Complex Required for Transport II
  • Endosomal Sorting Complex Required for Transport III

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Vesicular Transport Proteins (2001-2009)

MeSH Hierarchy

Tree Numbers

  1. D05.500w.199w
  2. D12.776w.543w.990w.493w

AMA Style

References

  1. National Library of Medicine. Endosomal Sorting Complexes Required for Transport. Medical Subject Headings (MeSH). 2026. Unique ID D056827. http://id.nlm.nih.gov/mesh/2026/D056827
  2. Endosomal Sorting Complexes Required for Transport. In: Wikipedia. https://en.wikipedia.org/wiki/ESCRT
  3. Endosomal Sorting Complexes Required for Transport. In: Wikidata. https://www.wikidata.org/wiki/Q22327705