Phenomena and Processes

Endophenotypes

Measurable biological (physiological, biochemical, and anatomical features), behavioral (psychometric pattern) or cognitive markers that are found more often in individuals with a disease than in the general population. Because many endophenotypes are present before the disease onset and in individuals with heritable risk for disease such as unaffected family members, they can be used to help diagnose and search for causative genes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Measurable biological (physiological, biochemical, and anatomical features), behavioral (psychometric pattern) or cognitive markers that are found more often in individuals with a disease than in the general population. Because many endophenotypes are present before the disease onset and in individuals with heritable risk for disease such as unaffected family members, they can be used to help diagnose and search for causative genes.

MeSH Record

Classification

Broader headings

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Synonyms

1 entry terms
  • Endophenotype

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings analysis, blood, cerebrospinal fluid, chemistry, metabolism, urine.

MeSH Record

History Note

2011

MeSH Record

Previous Indexing

  • Phenotype (2001-2010)

MeSH Hierarchy

Tree Number

  1. G05.695w.224w

AMA Style

References

  1. National Library of Medicine. Endophenotypes. Medical Subject Headings (MeSH). 2026. Unique ID D058068. http://id.nlm.nih.gov/mesh/2026/D058068
  2. Endophenotypes. In: Wikipedia. https://en.wikipedia.org/wiki/Endophenotype
  3. Endophenotypes. In: Wikidata. https://www.wikidata.org/wiki/Q2032061