Chemicals and Drugs

Endocrine Disruptors

Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

14 entry terms
  • Endocrine Disrupting Chemical
  • Endocrine Disrupting Chemicals
  • Endocrine Disruptor
  • Chemical, Endocrine Disrupting
  • Chemicals, Endocrine Disrupting
  • Disrupting Chemical, Endocrine
  • Disruptor, Endocrine
  • Disruptors, Endocrine
  • Endocrine Disruptor Effect
  • Endocrine Disruptor Effects
  • Disruptor Effect, Endocrine
  • Disruptor Effects, Endocrine
  • Effect, Endocrine Disruptor
  • Effects, Endocrine Disruptor

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

note entry term ENDOCRINE DISRUPTOR EFFECT: use only for the endocrine disruptor effect of a chemical substance

MeSH Record

History Note

2006

MeSH Record

Previous Indexing

  • Endocrine Glands/drug effects (1993-2005)
  • Endocrine System/drug effects (1997-2005)

MeSH Hierarchy

Tree Numbers

  1. D27.505.696.353w
  2. D27.888w.141w

AMA Style

References

  1. National Library of Medicine. Endocrine Disruptors. Medical Subject Headings (MeSH). 2026. Unique ID D052244. http://id.nlm.nih.gov/mesh/2026/D052244
  2. Endocrine Disruptors. In: Wikipedia. https://en.wikipedia.org/wiki/Endocrine_disruptor
  3. Endocrine Disruptors. In: Wikidata. https://www.wikidata.org/wiki/Q1138899