Chemicals and Drugs

Eledoisin

A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1364)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1364)

Chemical Identity

Chemical Information

Molecular Formula
C54H85N13O15S
Molecular Weight
1188.4 g/mol
CAS Registry No.
69-25-0
IUPAC Name
(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
InChIKey
AYLPVIWBPZMVSH-FCKMLYJASA-N
SMILES
CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCC(=O)N3
MeSH Unique ID
D004600
Source
PubChem CID 10328936

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

65(63)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.812w.900w.354w
  2. D12.644w.400w.800w.354w
  3. D12.644w.456w.800w.354w
  4. D12.776w.467.812w.900w.354w
  5. D12.776w.631w.650w.800w.354w
  6. D20.888w.590.325w
  7. D23.469.050w.375w.850w.275w
  8. D23.529.812w.900w.354w
  9. D23.946w.580.590.325w
  10. D23.946w.833w.590.325w

AMA Style

References

  1. National Library of Medicine. Eledoisin. Medical Subject Headings (MeSH). 2026. Unique ID D004600. http://id.nlm.nih.gov/mesh/2026/D004600
  2. Eledoisin. In: Wikipedia. https://en.wikipedia.org/wiki/Eledoisin
  3. Eledoisin. In: Wikidata. https://www.wikidata.org/wiki/Q5358600
  4. Eledoisin. In: PubChem Compound. CID 10328936. https://pubchem.ncbi.nlm.nih.gov/compound/10328936