Chemicals and Drugs

Elafin

A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A secretory proteinase inhibitory protein that was initially purified from human SKIN. It is found in a variety mucosal secretions and is present at high levels in SPUTUM. Elafin may play a role in the innate immunity (IMMUNITY, INNATE) response of the LUNG.

MeSH Record

Classification

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Peptidase Inhibitor 3, Skin-derived
  • Protease Inhibitor 3, Skin-derived
  • Protease Inhibitor WAP3
  • Skin-Derived Antileukoproteinase
  • Antileukoproteinase, Skin-Derived
  • Inhibitor WAP3, Protease
  • Peptidase Inhibitor 3, Skin derived
  • Protease Inhibitor 3, Skin derived
  • Skin Derived Antileukoproteinase

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(2005)

MeSH Record

Previous Indexing

  • Protease Inhibitors (1990-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Elafin. Medical Subject Headings (MeSH). 2026. Unique ID D053492. http://id.nlm.nih.gov/mesh/2026/D053492
  2. Elafin. In: Wikipedia. https://en.wikipedia.org/wiki/Elafin
  3. Elafin. In: Wikidata. https://www.wikidata.org/wiki/Q5353128