Chemicals and Drugs

Early Growth Response Protein 2

An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.

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Classification

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Synonyms

6 entry terms
  • EGR2 Transcription Factor
  • Krox-20 Transcription Factor
  • Krox20 Protein
  • Krox 20 Transcription Factor
  • Transcription Factor, EGR2
  • Transcription Factor, Krox-20

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1988)

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AMA Style

References

  1. National Library of Medicine. Early Growth Response Protein 2. Medical Subject Headings (MeSH). 2026. Unique ID D051767. http://id.nlm.nih.gov/mesh/2026/D051767
  2. Early Growth Response Protein 2. In: Wikidata. https://www.wikidata.org/wiki/Q21110101