Structured Summary
Abstract
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.
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Broader headings
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Synonyms
5 entry terms
- E2F Transcription Factor 6 Protein
- Transcription Factor E2F-6
- E2F-6, Transcription Factor
- Transcription Factor E2F 6
- Transcription Factor, E2F6
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
see SCR for organism-specific terms
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History Note
2006(2004)
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1991-2005)
- DNA-Binding Proteins (1991-2005)
- Transcription Factors (1991-2005)
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AMA Style
References
- National Library of Medicine. E2F6 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D050701. http://id.nlm.nih.gov/mesh/2026/D050701
- E2F6 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q21130594