Structured Summary
Abstract
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F4 recruits chromatin remodeling factors indirectly to target gene PROMOTER REGIONS through RETINOBLASTOMA LIKE PROTEIN P130 and RETINOBLASTOMA LIKE PROTEIN P107.
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Broader headings
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Synonyms
10 entry terms
- E2F Transcription Factor 4 Protein
- E2F-4 Protein
- E2F-4 Transcription Factor
- Transcription Factor E2F-4
- E2F 4 Protein
- E2F 4 Transcription Factor
- E2F-4, Transcription Factor
- Transcription Factor E2F 4
- Transcription Factor, E2F-4
- Transcription Factor, E2F4
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
see SCR for organism-specific terms
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History Note
2006(1994)
MeSH Record
Previous Indexing
- DNA-Binding Proteins (1994-2005)
- Transcription Factors (1994-2005)
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AMA Style
References
- National Library of Medicine. E2F4 Transcription Factor. Medical Subject Headings (MeSH). 2026. Unique ID D050704. http://id.nlm.nih.gov/mesh/2026/D050704
- E2F4 Transcription Factor. In: Wikidata. https://www.wikidata.org/wiki/Q21105842